MBQ-167 as a Dual Rac/Cdc42 Inhibitor in Metastatic Cancer
Rho GTPases participate in the regulation of cell migration, invasion, apoptosis, cell-to-cell and cell-to-extracellular matrix adhesions. The Rho GTPases Rac and Cdc42 potently induce actin polymerization. In addition, Cdc42 plays a…