Product Name : Irinotecan-d10Description:Irinotecan-d10 ((+)-Irinotecan-d10) is a deuterium labeled Irinotecan ((+)-Irinotecan). Irinotecan ((+)-Irinotecan) is a topoisomerase I inhibitor, preventing religation of the DNA strand by binding to topoisomerase I-DNA complex.CAS:…
Product Name : Tedizolid phosphateDescription:Tedizolid phosphate (TR-701FA) is a novel oxazolidinone with activity against Gram-positive pathogens.CAS: 856867-55-5Molecular Weight:450.32Formula: C17H16FN6O6PChemical Name: {phenyl}-2-oxo-1,3-oxazolidin-5-yl]methoxy}phosphonic acidSmiles : CN1N=C(N=N1)C1=CC=C(C=N1)C1=CC=C(C=C1F)N1C(COP(O)(O)=O)OC1=OInChiKey: QCGUSIANLFXSGE-GFCCVEGCSA-NInChi : InChI=1S/C17H16FN6O6P/c1-23-21-16(20-22-23)15-5-2-10(7-19-15)13-4-3-11(6-14(13)18)24-8-12(30-17(24)25)9-29-31(26,27)28/h2-7,12H,8-9H2,1H3,(H2,26,27,28)/t12-/m1/s1Purity: ≥98% (or refer…
Product Name : H-D-cis-Hyp-OHDescription:cis-4-Hydroxy-D-proline is a precursor of conformationally restricted PNA adenine monomer. cis-4-Hydroxy-D-proline can be used to study the specificity and kinetics of D-alanine dehydrogenase.CAS: 2584-71-6Molecular Weight:131.13Formula: C5H9NO3Chemical Name:…
Product Name : MCC-DM1Description:MCC-DM1 is a drug-Linker Conjugates for ADC such ad Anti-CD22-MCC-DM1.CAS: 1100692-14-5Molecular Weight:974.55Formula: C47H64ClN5O13SChemical Name: (1S, 2R, 3S, 5S, 6S, 20R, 21S)-11-chloro-21-hydroxy-12, 20-dimethoxy-2, 5, 9, 16-tetramethyl-8, 23-dioxo-4, 24-dioxa-9,…
Product Name : cIAP1 Ligand-Linker Conjugates 9Description:cIAP1 Ligand-Linker Conjugates 9 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 9 can be used…
Product Name : MK2-IN-1Description:MK2-IN-1 is a potent and selecitve MAPKAPK2(MK2) inhibitor(IC50=0.11 uM) with a non-ATP competitive binding mode.IC50 value: 0.11 uM Target: MAPKAPK2(MK2) inhibitorMK2-IN-1 was profiled for kinase selectivity by…
Product Name : Salidroside(Rhodioloside)Description:Salidroside is a prolyl endopeptidase Inhibitor. Salidroside alleviates cachexia symptoms in mouse models of cancer cachexia via activating mTOR signalling. Salidroside protects dopaminergic neurons by enhancing PINK1/Parkin-mediated…
Product Name : MCU i4Description:MCU i4 is a negative modulator of mitochondrial calcium (Ca2+) uniporter (MCU) complex, which binds to MICU1, a regulatory protein within MCU complex. MCU i4 reduces…
Product Name : KO-947Description:KO-947 is a potent and selective inhibitor of ERK1/2 kinases. KO-947 blocks ERK signaling and proliferation of tumor cells exhibiting dysregulation of MAPK pathway signaling at low…
Product Name : AZD-2461Description:AZD2461 is a novel and potent PARP inhibitor with lower affinity to P-glycoprotein. AZD2641 is currently in Phase I clinical study. The study is being conducted to…