However, the variation in serum concentrations of E2 may not accurately reflect intraprostatic levels, because E2 is produced from T by the enzyme aromatase
The most powerful androgen in the prostate is 5a-dihydrotestosterone (DHT), acquired from circulating testosterone (T) by the enzyme 5a-Reductase (5a-R, EC 1.3.99.5), which is expressed as a few isozymes, kinds…