(R,R)-CFT8634
Product Name : (R,R)-CFT8634Description:(R, R)-CFT8634 is a selective and orally active BRD9 protein degrader. (R, R)-CFT8634 has the potential for the research of disorders mediated by BRD9, including but not…
Lp-PLA2-IN-2
Product Name : Lp-PLA2-IN-2Description:Lp-PLA2-IN-2 is a potent and selective lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor, with an IC50 0f 120 nM for recombinant human Lp-PLA2.CAS: 2071636-15-0Molecular Weight:394.46Formula: C19H23FN2O4SChemical Name: 2-fluoro-5-{2-ethoxy}benzonitrileSmiles :…
VU0810464
Product Name : VU0810464Description:VU0810464 is a potent and selective non-ureaG protein-gated inwardly-rectifying potassium channels (GIRK, Kir3) activator. VU0810464 displays nanomolar potency for neuronal (EC50=165 nM) and GIRK1/4 (EC50=720 nM) channels…
Acoramidis
Product Name : AcoramidisDescription:Acoramidis (AG10) is an orally active and selective kinetic stabilizer of WT and V122I-TTR (transthyretin). Acoramidis (AG10) is used in the study for transthyretin amyloidosis.CAS: 1446711-81-4Molecular Weight:292.31Formula:…
ZL0580
Product Name : ZL0580Description:ZL0580, a structurally close analog of ZL0590, induces epigenetic suppression of HIV via selectively binding to BD1 domain of BRD4. ZL0580 induces HIV suppression by inhibiting Tat…
PD 404182
Product Name : PD 404182Description:PD 404182 is a potent and competitive inhibitor of human dimethylarginine dimethylaminohydrolase 1 (DDAH1), with an IC50 of 9 μM. PD 404182 exhibits antiangiogenic and antiviral…
Azido-PEG2-CH2COOH
Product Name : Azido-PEG2-CH2COOHDescription:Azido-PEG2-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.CAS: 882518-90-3Molecular Weight:189.17Formula: C6H11N3O4Chemical Name: 2-acetic acidSmiles : ==NCCOCCOCC(O)=OInChiKey: OCIIYNXOTJRSHW-UHFFFAOYSA-NInChi : InChI=1S/C6H11N3O4/c7-9-8-1-2-12-3-4-13-5-6(10)11/h1-5H2,(H,10,11)Purity: ≥98% (or…
Tri-(PEG1-C2-acid)
Product Name : Tri-(PEG1-C2-acid)Description:Tri-(PEG1-C2-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.CAS: 1381861-95-5Molecular Weight:365.38Formula: C15H27NO9Chemical Name: 3-(2-{bisamino}ethoxy)propanoic acidSmiles : OC(=O)CCOCCN(CCOCCC(O)=O)CCOCCC(O)=OInChiKey: QNHMUDRSUKYNFE-UHFFFAOYSA-NInChi : InChI=1S/C15H27NO9/c17-13(18)1-7-23-10-4-16(5-11-24-8-2-14(19)20)6-12-25-9-3-15(21)22/h1-12H2,(H,17,18)(H,19,20)(H,21,22)Purity: ≥98%…
MS4077
Product Name : MS4077Description:MS4077 is an anaplastic lymphoma kinase (ALK) PROTAC (degrader) with a Kd of 37 nM for binding affinity to ALK.CAS: 2230077-10-6Molecular Weight:1134.73Formula: C55H72ClN9O13SChemical Name: 2-(4-{4-amino}pyrimidin-2-yl)amino]-2-methyl-5-(propan-2-yloxy)phenyl}piperidin-1-yl)-N-(17-{amino}-3,6,9,12,15-pentaoxaheptadecan-1-yl)acetamideSmiles : CC1=CC(NC2=NC(NC3=CC=CC=C3S(=O)(=O)C(C)C)=C(Cl)C=N2)=C(C=C1C1CCN(CC(=O)NCCOCCOCCOCCOCCOCCNC2=CC=CC3=C2C(=O)N(C2CCC(=O)NC2=O)C3=O)CC1)OC(C)CInChiKey: VEKJQNCZEPLNJF-UHFFFAOYSA-NInChi…
Nisoldipine-d4
Product Name : Nisoldipine-d4Description:Nisoldipine-d4 (BAY-k 5552-d4) is the deuterium labeled Nisoldipine. Nisoldipine(BAY-k 5552) is a calcium channel blocker belonging to the dihydropyridines class, specific for L-type Cav1.2 with IC50 of…