EIF2a phosphorylation coincides with a marked decrease in global translation in parasites uncovered to a combined temperature and acidic anxiety (Determine 1) or during amastigote differentiation in vitro (Figure 3A)

Reduce in General Translation upon Anxiety and throughout Leishmania Amastigote Differentiation Correlates with eIF2a Phosphorylation We subsequent investigated whether attenuation of general translation i186692-46-6n L. infantum axenic amastigotes is connected…