The downstream targets of Prlr/Jak2/Stat5B signaling in b-cells include insulin, glucose transporter 2 (Glut2), glucokinase (Gck), tryptophan hydroxylase one (Tph1), cyclin D2 (Ccnd2) and Prlr [6,7]. In addition, prolactin signaling may possibly also be involved
We evaluated 1 of these candidates, SLPI, on the protein amount in plasma and urine of the transplant recipients. We could affirm the substantially elevated SLPI mRNA expression in hurt…