Product Name :
BCR-ABL-IN-1

Description:
BCR-ABL-IN-1 is an inhibitor of BCR-ABL tyrosine kinase, with a pIC50 of 6.46, and may be used in the research of chronic myelogenous leukemia.

CAS:
188260-50-6

Molecular Weight:
459.44

Formula:
C23H21F4N5O

Chemical Name:
4-[1-(3-aminopropyl)-1H-indol-4-yl]-N-[3-(1,1,2,2-tetrafluoroethoxy)phenyl]pyrimidin-2-amine

Smiles :
NCCCN1C=CC2C(=CC=CC1=2)C1C=CN=C(NC2C=C(C=CC=2)OC(F)(F)C(F)F)N=1

InChiKey:
HNAIZJDQDDXEGC-UHFFFAOYSA-N

InChi :
InChI=1S/C23H21F4N5O/c24-21(25)23(26,27)33-16-5-1-4-15(14-16)30-22-29-11-8-19(31-22)17-6-2-7-20-18(17)9-13-32(20)12-3-10-28/h1-2,4-9,11,13-14,21H,3,10,12,28H2,(H,29,30,31)

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life:
≥12 months if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.Tolebrutinib Epigenetic Reader Domain

Additional information:
BCR-ABL-IN-1 is an inhibitor of BCR-ABL tyrosine kinase, with a pIC50 of 6.Monepantel Membrane Transporter/Ion Channel 46, and may be used in the research of chronic myelogenous leukemia.|Product information|CAS Number: 188260-50-6|Molecular Weight: 459.44|Formula: C23H21F4N5O|Chemical Name: 4-[1-(3-aminopropyl)-1H-indol-4-yl]-N-[3-(1,1,2,2-tetrafluoroethoxy)phenyl]pyrimidin-2-amine|Smiles: NCCCN1C=CC2C(=CC=CC1=2)C1C=CN=C(NC2C=C(C=CC=2)OC(F)(F)C(F)F)N=1|InChiKey: HNAIZJDQDDXEGC-UHFFFAOYSA-N|InChi: InChI=1S/C23H21F4N5O/c24-21(25)23(26,27)33-16-5-1-4-15(14-16)30-22-29-11-8-19(31-22)17-6-2-7-20-18(17)9-13-32(20)12-3-10-28/h1-2,4-9,11,13-14,21H,3,10,12,28H2,(H,29,30,31)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:32962420 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|BCR-ABL-IN-1 (Compound 21) is an inhibitor of BCR-ABL tyrosine kinase, with a pIC50 of 6.46, and may be used in the research of chronic myelogenous leukemia.|Products are for research use only. Not for human use.|

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