Product Name :
Z-Leu-Leu-Leu-vinyl sulfone
Sequence:
Z-(Leu)3-vinyl sulfone
Purity:
≥99%
Molecular Weight:
~551.3 Da
Solubility :
Appearance:
Use/Stability :
As indicated on product label or CoA when stored as recommended.
Description:
Inhibits the trypsin-like, chymotrypsin-like and caspase-like (PGPH) activity in isolated proteasomes and living cells by covalent modification of the amino-terminal threonine of the catalytically active β subunits. The vinyl sulfone acts as a Michael acceptor for soft nucleophiles such as thiols, leading to the formation of a covalent bond, while being resistant to attack by free thiols, which can cause inactivation of other classes of protease inhibitors.177332-37-5 medchemexpress
CAS :
Solubility:
Formula:
Additional Information :
| MW ~551.26305-03-3 web 3 Da | Purity ≥99% | Sequence Z-(Leu)3-vinyl sulfone