Product Name :
DRI-C21045
Description:
DRI-C21045 (compound 10) is a potent and selective inhibitor of the CD40-CD40L costimulatory protein-protein interaction (PPI) with an IC50 of 0.17 µM. DRI-C21045 shows concentration-dependent inhibition of the activation of NF-κB and B cell proliferation all induced by CD40L with IC50s of 17.1 µM and 4.5 µM, respectively.
CAS:
2101765-81-3
Molecular Weight:
580.61
Formula:
C32H24N2O7S
Chemical Name:
8-{4′-[4-(methoxycarbonyl)benzamido]-[1,1′-biphenyl]-4-amido}naphthalene-1-sulfonic acid
Smiles :
COC(=O)C1C=CC(=CC=1)C(=O)NC1C=CC(=CC=1)C1C=CC(=CC=1)C(=O)NC1=CC=CC2=CC=CC(=C21)S(O)(=O)=O
InChiKey:
BZAWLSZPOBGURT-UHFFFAOYSA-N
InChi :
InChI=1S/C32H24N2O7S/c1-41-32(37)25-14-12-23(13-15-25)30(35)33-26-18-16-21(17-19-26)20-8-10-24(11-9-20)31(36)34-27-6-2-4-22-5-3-7-28(29(22)27)42(38,39)40/h2-19H,1H3,(H,33,35)(H,34,36)(H,38,39,40)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Nemonoxacin} MedChemExpress|{Nemonoxacin} Anti-infection|{Nemonoxacin} Technical Information|{Nemonoxacin} Data Sheet|{Nemonoxacin} supplier|{Nemonoxacin} Epigenetics}
Shelf Life:
≥12 months if stored properly.{{Acarbose} MedChemExpress|{Acarbose} Metabolic Enzyme/Protease|{Acarbose} Technical Information|{Acarbose} Data Sheet|{Acarbose} custom synthesis|{Acarbose} Epigenetic Reader Domain}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
DRI-C21045 (compound 10) is a potent and selective inhibitor of the CD40-CD40L costimulatory protein-protein interaction (PPI) with an IC50 of 0.PMID:33108912 17 µM. DRI-C21045 shows concentration-dependent inhibition of the activation of NF-κB and B cell proliferation all induced by CD40L with IC50s of 17.1 µM and 4.5 µM, respectively.|Product information|CAS Number: 2101765-81-3|Molecular Weight: 580.61|Formula: C32H24N2O7S|Chemical Name: 8-{4′-[4-(methoxycarbonyl)benzamido]-[1,1′-biphenyl]-4-amido}naphthalene-1-sulfonic acid|Smiles: COC(=O)C1C=CC(=CC=1)C(=O)NC1C=CC(=CC=1)C1C=CC(=CC=1)C(=O)NC1=CC=CC2=CC=CC(=C21)S(O)(=O)=O|InChiKey: BZAWLSZPOBGURT-UHFFFAOYSA-N|InChi: InChI=1S/C32H24N2O7S/c1-41-32(37)25-14-12-23(13-15-25)30(35)33-26-18-16-21(17-19-26)20-8-10-24(11-9-20)31(36)34-27-6-2-4-22-5-3-7-28(29(22)27)42(38,39)40/h2-19H,1H3,(H,33,35)(H,34,36)(H,38,39,40)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 2 mg/mL (3.44 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|