Product Name :
MCU i4
Description:
MCU i4 is a negative modulator of mitochondrial calcium (Ca2+) uniporter (MCU) complex, which binds to MICU1, a regulatory protein within MCU complex. MCU i4 reduces mitochondrial Ca2+ uptake in multiple cell lines including MEFs, MDA-MB,231 and HEK293T cells, and demonstrates a negative effect on mitochondrial membrane potential. In ex vivo muscle fibres, MCU i4 reduces mitochondrial Ca2+ uptake and impairs muscle cell growth.
CAS:
371924-24-2
Molecular Weight:
377.48
Formula:
C23H27N3O2
Chemical Name:
Ethyl 4-((4-(diethylamino)phenyl)amino)-6-methylquinoline-3-carboxylate
Smiles :
CC1C=C2C(=CC=1)N=CC(C(=O)OCC)=C2NC1C=CC(=CC=1)N(CC)CC
InChiKey:
RIWXBJCWHVMATR-UHFFFAOYSA-N
InChi :
InChI=1S/C23H27N3O2/c1-5-26(6-2)18-11-9-17(10-12-18)25-22-19-14-16(4)8-13-21(19)24-15-20(22)23(27)28-7-3/h8-15H,5-7H2,1-4H3,(H,24,25)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Etesevimab} site|{Etesevimab} SARS-CoV|{Etesevimab} Purity & Documentation|{Etesevimab} References|{Etesevimab} supplier|{Etesevimab} Epigenetic Reader Domain}
Shelf Life:
≥12 months if stored properly.{{Oleandrin} medchemexpress|{Oleandrin} Membrane Transporter/Ion Channel|{Oleandrin} Protocol|{Oleandrin} In stock|{Oleandrin} custom synthesis|{Oleandrin} Epigenetic Reader Domain}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:23310954
Additional information:
MCU i4 is a negative modulator of mitochondrial calcium (Ca2+) uniporter (MCU) complex, which binds to MICU1, a regulatory protein within MCU complex. MCU i4 reduces mitochondrial Ca2+ uptake in multiple cell lines including MEFs, MDA-MB,231 and HEK293T cells, and demonstrates a negative effect on mitochondrial membrane potential. In ex vivo muscle fibres, MCU i4 reduces mitochondrial Ca2+ uptake and impairs muscle cell growth.|Product information|CAS Number: 371924-24-2|Molecular Weight: 377.48|Formula: C23H27N3O2|Synonym:|MCUi4|MCU-i4|Chemical Name: Ethyl 4-((4-(diethylamino)phenyl)amino)-6-methylquinoline-3-carboxylate|Smiles: CC1C=C2C(=CC=1)N=CC(C(=O)OCC)=C2NC1C=CC(=CC=1)N(CC)CC|InChiKey: RIWXBJCWHVMATR-UHFFFAOYSA-N|InChi: InChI=1S/C23H27N3O2/c1-5-26(6-2)18-11-9-17(10-12-18)25-22-19-14-16(4)8-13-21(19)24-15-20(22)23(27)28-7-3/h8-15H,5-7H2,1-4H3,(H,24,25)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: Soluble in DMSO|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|