Product Name :
PF-03463275
Description:
PF-03463275 is a centrally penetrant, orally available, selective, and competitive GlyT1 (glycine transporter-1) reversible inhibitor, with a Ki of 11.6 nM. PF-03463275 has the potential for Schizophrenia research.
CAS:
1173239-39-8
Molecular Weight:
376.86
Formula:
C19H22ClFN4O
Chemical Name:
N-[(3-chloro-4-fluorophenyl)methyl]-1-methyl-N-{[(1R,5S)-3-methyl-3-azabicyclo[3.1.0]hexan-6-yl]methyl}-1H-imidazole-4-carboxamide
Smiles :
CN1C[C@@H]2[C@H](C1)C2CN(CC1=CC(Cl)=C(F)C=C1)C(=O)C1=CN(C)C=N1
InChiKey:
KYLOBHXXQOZRKK-YIONKMFJSA-N
InChi :
InChI=1S/C19H22ClFN4O/c1-23-7-13-14(8-23)15(13)9-25(19(26)18-10-24(2)11-22-18)6-12-3-4-17(21)16(20)5-12/h3-5,10-11,13-15H,6-9H2,1-2H3/t13-,14+,15?
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Chloroprocaine} site|{Chloroprocaine} Membrane Transporter/Ion Channel|{Chloroprocaine} Technical Information|{Chloroprocaine} In stock|{Chloroprocaine} custom synthesis|{Chloroprocaine} Cancer}
Shelf Life:
≥12 months if stored properly.{{Umeclidinium} medchemexpress|{Umeclidinium} mAChR|{Umeclidinium} Biological Activity|{Umeclidinium} In Vivo|{Umeclidinium} supplier|{Umeclidinium} Autophagy}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:23415682
Additional information:
PF-03463275 is a centrally penetrant, orally available, selective, and competitive GlyT1 (glycine transporter-1) reversible inhibitor, with a Ki of 11.6 nM. PF-03463275 has the potential for Schizophrenia research.|Product information|CAS Number: 1173239-39-8|Molecular Weight: 376.86|Formula: C19H22ClFN4O|Chemical Name: N-[(3-chloro-4-fluorophenyl)methyl]-1-methyl-N-{[(1R,5S)-3-methyl-3-azabicyclo[3.1.0]hexan-6-yl]methyl}-1H-imidazole-4-carboxamide|Smiles: CN1C[C@@H]2[C@H](C1)C2CN(CC1=CC(Cl)=C(F)C=C1)C(=O)C1=CN(C)C=N1|InChiKey: KYLOBHXXQOZRKK-YIONKMFJSA-N|InChi: InChI=1S/C19H22ClFN4O/c1-23-7-13-14(8-23)15(13)9-25(19(26)18-10-24(2)11-22-18)6-12-3-4-17(21)16(20)5-12/h3-5,10-11,13-15H,6-9H2,1-2H3/t13-,14+,15?|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 33.33 mg/mL (88.44 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vivo:|PF-03463275 (1-10 mg/kg; s.c.) attenuates oscillatory potentials (OPs).|Products are for research use only. Not for human use.|