Product Name :
L67
Description:
L67 is a novel, competitive human DNA ligase inhibitor, inhibits DNA ligases I and III with IC50 of 10 μM and 10 μM.IC50 value: 10 μM Target: DNA ligasesin vitro: L67 significantly increases the cytotoxicity of DNA damaging agents. L67 also inhibits cell proliferation.
CAS:
325970-71-6
Molecular Weight:
486.11
Formula:
C16H14Br2N4O4
Chemical Name:
2-[(3,5-dibromo-4-methylphenyl)amino]-N’-[(1E)-(2-hydroxy-5-nitrophenyl)methylidene]acetohydrazide
Smiles :
CC1C(Br)=CC(=CC=1Br)NCC(=O)N/N=C/C1=CC(=CC=C1O)[N+]([O-])=O
InChiKey:
KFEPVFJQVOMODD-IFRROFPPSA-N
InChi :
InChI=1S/C16H14Br2N4O4/c1-9-13(17)5-11(6-14(9)18)19-8-16(24)21-20-7-10-4-12(22(25)26)2-3-15(10)23/h2-7,19,23H,8H2,1H3,(H,21,24)/b20-7+
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Brimonidine medchemexpress
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
L67 is a novel, competitive human DNA ligase inhibitor, inhibits DNA ligases I and III with IC50 of 10 μM and 10 μM.IC50 value: 10 μM Target: DNA ligasesin vitro: L67 significantly increases the cytotoxicity of DNA damaging agents. L67 also inhibits cell proliferation.|Product information|CAS Number: 325970-71-6|Molecular Weight: 486.11|Formula: C16H14Br2N4O4|Chemical Name: 2-[(3,5-dibromo-4-methylphenyl)amino]-N’-[(1E)-(2-hydroxy-5-nitrophenyl)methylidene]acetohydrazide|Smiles: CC1C(Br)=CC(=CC=1Br)NCC(=O)N/N=C/C1=CC(=CC=C1O)[N+]([O-])=O|InChiKey: KFEPVFJQVOMODD-IFRROFPPSA-N|InChi: InChI=1S/C16H14Br2N4O4/c1-9-13(17)5-11(6-14(9)18)19-8-16(24)21-20-7-10-4-12(22(25)26)2-3-15(10)23/h2-7,19,23H,8H2,1H3,(H,21,24)/b20-7+|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : ≥ 33 mg/mL (67.Aliskiren MedChemExpress 89 mM).PMID:31634248 H2O : 1 mg/mL (2.06 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|