Product Name :
AZ876

Description:
AZ876 is a potent and high-affinity LXR agonist. AZ876 displays 25-fold and 2.5-fold more potent than GW3965 (HY-10627) on human (h)LXRα and hLXRβ respectively.

CAS:
898800-26-5

Molecular Weight:
439.57

Formula:
C24H29N3O3S

Chemical Name:
2-tert-butyl-5-phenyl-4-[4-(piperidin-1-yl)phenyl]amino-2,3-dihydro-1λ⁶,2-thiazole-1,1,3-trione

Smiles :
CC(C)(C)N1C(=O)C(NC2C=CC(=CC=2)N2CCCCC2)=C(C2C=CC=CC=2)S1(=O)=O

InChiKey:
IVANYIPLGFVBGR-UHFFFAOYSA-N

InChi :
InChI=1S/C24H29N3O3S/c1-24(2,3)27-23(28)21(22(31(27,29)30)18-10-6-4-7-11-18)25-19-12-14-20(15-13-19)26-16-8-5-9-17-26/h4,6-7,10-15,25H,5,8-9,16-17H2,1-3H3

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.KRASG12D-IN-2 manufacturer

Shelf Life:
≥12 months if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.

Additional information:
AZ876 is a potent and high-affinity LXR agonist. AZ876 displays 25-fold and 2.5-fold more potent than GW3965 (HY-10627) on human (h)LXRα and hLXRβ respectively.|Product information|CAS Number: 898800-26-5|Molecular Weight: 439.5-Bromotetralone Epigenetic Reader Domain 57|Formula: C24H29N3O3S|Chemical Name: 2-tert-butyl-5-phenyl-4-[4-(piperidin-1-yl)phenyl]amino-2,3-dihydro-1λ⁶,2-thiazole-1,1,3-trione|Smiles: CC(C)(C)N1C(=O)C(NC2C=CC(=CC=2)N2CCCCC2)=C(C2C=CC=CC=2)S1(=O)=O|InChiKey: IVANYIPLGFVBGR-UHFFFAOYSA-N|InChi: InChI=1S/C24H29N3O3S/c1-24(2,3)27-23(28)21(22(31(27,29)30)18-10-6-4-7-11-18)25-19-12-14-20(15-13-19)26-16-8-5-9-17-26/h4,6-7,10-15,25H,5,8-9,16-17H2,1-3H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 100 mg/mL (227.PMID:32508138 50 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|

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