Product Name :
m-PEG6-2-methylacrylate
Description:
m-PEG6-2-methylacrylate is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
CAS:
90784-86-4
Molecular Weight:
364.43
Formula:
C17H32O8
Chemical Name:
2,5,8,11,14,17-hexaoxanonadecan-19-yl 2-methylprop-2-enoate
Smiles :
CC(=C)C(=O)OCCOCCOCCOCCOCCOCCOC
InChiKey:
FVSGBTSAXJGUNZ-UHFFFAOYSA-N
InChi :
InChI=1S/C17H32O8/c1-16(2)17(18)25-15-14-24-13-12-23-11-10-22-9-8-21-7-6-20-5-4-19-3/h1,4-15H2,2-3H3
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Taurochenodeoxycholic acid Purity
Shelf Life:
≥12 months if stored properly.Tyloxapol Purity
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
m-PEG6-2-methylacrylate is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.|Product information|CAS Number: 90784-86-4|Molecular Weight: 364.43|Formula: C17H32O8|Chemical Name: 2,5,8,11,14,17-hexaoxanonadecan-19-yl 2-methylprop-2-enoate|Smiles: CC(=C)C(=O)OCCOCCOCCOCCOCCOCCOC|InChiKey: FVSGBTSAXJGUNZ-UHFFFAOYSA-N|InChi: InChI=1S/C17H32O8/c1-16(2)17(18)25-15-14-24-13-12-23-11-10-22-9-8-21-7-6-20-5-4-19-3/h1,4-15H2,2-3H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:32870256 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|References:|Zhu C, et al. Reversibly shielded DNA polyplexes based on bioreducible PDMAEMA-SS-PEG-SS-PDMAEMA triblock copolymers mediate markedly enhanced nonviral gene transfection. Biomacromolecules. 2012 Mar 12;13(3):769-78.Products are for research use only. Not for human use.|