Product Name :
Br-PEG4-acid
Description:
Br-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
CAS:
Molecular Weight:
315.16
Formula:
C10H19BrO6
Chemical Name:
14-bromo-3,6,9,12-tetraoxatetradecanoic acid
Smiles :
OC(=O)COCCOCCOCCOCCBr
InChiKey:
GNHQMWDLFMWZTA-UHFFFAOYSA-N
InChi :
InChI=1S/C10H19BrO6/c11-1-2-14-3-4-15-5-6-16-7-8-17-9-10(12)13/h1-9H2,(H,12,13)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.Delamanid Cancer
Additional information:
Br-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.|Product information|Molecular Weight: 315.16|Formula: C10H19BrO6|Chemical Name: 14-bromo-3,6,9,12-tetraoxatetradecanoic acid|Smiles: OC(=O)COCCOCCOCCOCCBr|InChiKey: GNHQMWDLFMWZTA-UHFFFAOYSA-N|InChi: InChI=1S/C10H19BrO6/c11-1-2-14-3-4-15-5-6-16-7-8-17-9-10(12)13/h1-9H2,(H,12,13)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: To be determined|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.Eicosapentaenoic Acid Metabolic Enzyme/Protease |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.PMID:32644370 PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|References:|An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562Products are for research use only. Not for human use.|