Product Name :
Leukotriene C4
Sequence:
Purity:
≥95% (HPLC)
Molecular Weight:
625.8
Solubility :
Appearance:
Colorless solution.
Use/Stability :
As indicated on product label or CoA when stored as recommended. Stable for at least 1 year after receipt when stored, as supplied, at -80°C. Protect from exposure to air. Open ampule and aliquot into suitable tubes or vials. Store at -80°C or colder. For experiments with cells or tissues, aliquots of stock solutions may be evaporated to near dryness under a stream of nitrogen and dissolved in ethanol.{{402616-26-6} site|{402616-26-6} Biological Activity|{402616-26-6} In Vivo|{402616-26-6} manufacturer} Stock solutions may be used directly for HPLC analysis.
Description:
Prostanoid receptor ligand A cysteinyl leukotriene which acts as potent agonist for contraction of smooth muscle.{{908112-43-6} medchemexpress|{908112-43-6} Biological Activity|{908112-43-6} In stock|{908112-43-6} manufacturer} Induces microvascular permeability and mucus secretion in airways.PMID:29630197 Enhances growth of human airway epithelial cells. Reduces myocardial contractility and coronary blood flow. Induces long lasting hypotension. Stimulates angiogenesis. Stimulates LH8, LHRH9 and prolactin release. Produced in specific cell types or by transcellular biosynthesis and rapidly metabolized to LTD4 and LTE4. Transported by the multidrug resistance protein (MRP; Km=35nM).
CAS :
72025-60-6
Solubility:
Formula:
C30H47N3O9S
Additional Information :
| Alternative Name LTC4, 5S-Hydroxy-6R-(S-glutathionyl)-7E,9E,11Z,14Z-eicosatetraenoic acid | Appearance Colorless solution. | CAS 72025-60-6 | Couple Target Leukotriene receptor, Prostanoid receptor | Couple Type Ligand | Formula C30H47N3O9S | Formulation Liquid. In methanol/ammonium acetate buffer, 65:35 pH=5.6. | MI 14: 5455 | MW 625.8 | Purity ≥95% (HPLC) | Source Synthetic. | Unit of Measure (UM) µg