Product Name :
umbralisib (TGR-1202)
CAS No.:
1532533-67-7
Purity :
> 99%
Shipping:
Shipped on dry ice.
Storage :
Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month
SMILES:
CC(C)OC1=C(F)C=C(C=C1)C2=N[N](C(C)C3=C(C4=CC(=CC=C4)F)C(=O)C5=CC(=CC=C5O3)F)C6=C2C(=NC=N6)N
Product Description :
TGR-1202, a novel, next generation PI3Kδ inhibitor, inhibits PI3Kδ activity in enzyme and cell based assays with IC50 and EC50 values of 22.{{58944-73-3} web|{58944-73-3} Biological Activity|{58944-73-3} In Vivo|{58944-73-3} manufacturer} 2 & 24.{{1268524-70-4} MedChemExpress|{1268524-70-4} Protocol|{1268524-70-4} References|{1268524-70-4} manufacturer} 3 nM, respectively.PMID:30855818
Formula:
C31H24F3N5O3
Molecular Weight :
571.55
Synonyms:
Rp-5264
Additional Information:
|CAS No. 1532533-67-7 ; |Synonyms Rp-5264 ; |Formula C31H24F3N5O3 ; |Molecular Weight 571.55 ; |SMILES CC(C)OC1=C(F)C=C(C=C1)C2=N[N](C(C)C3=C(C4=CC(=CC=C4)F)C(=O)C5=CC(=CC=C5O3)F)C6=C2C(=NC=N6)N ; |Target PI3Kδ ; |Product Description TGR-1202, a novel, next generation PI3Kδ inhibitor, inhibits PI3Kδ activity in enzyme and cell based assays with IC50 and EC50 values of 22.2 & 24.3 nM, respectively. ; |Purity > 99% ; |Shipping Shipped on dry ice. ; |Storage Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month ; |Solubility Overview Soluble in DMSO