Product Name :
Apalutamide-COOH

Description:
Apalutamide-COOH can be used to synthesis Apalutamide. Apalutamide is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM.

CAS:
1332391-04-4

Molecular Weight:
464.39

Formula:
C20H12F4N4O3S

Chemical Name:
4-{7-[6-cyano-5-(trifluoromethyl)pyridin-3-yl]-8-oxo-6-sulfanylidene-5,7-diazaspiro[3.4]octan-5-yl}-2-fluorobenzoic acid

Smiles :
N#CC1=NC=C(C=C1C(F)(F)F)N1C(=S)N(C2=CC(F)=C(C=C2)C(O)=O)C2(CCC2)C1=O

InChiKey:
ICXCBGDFYFFSGX-UHFFFAOYSA-N

InChi :
InChI=1S/C20H12F4N4O3S/c21-14-7-10(2-3-12(14)16(29)30)28-18(32)27(17(31)19(28)4-1-5-19)11-6-13(20(22,23)24)15(8-25)26-9-11/h2-3,6-7,9H,1,4-5H2,(H,29,30)

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Vericiguat} medchemexpress|{Vericiguat} GPCR/G Protein|{Vericiguat} Purity & Documentation|{Vericiguat} References|{Vericiguat} manufacturer|{Vericiguat} Epigenetic Reader Domain}

Shelf Life:
≥12 months if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.

Additional information:
Apalutamide-COOH can be used to synthesis Apalutamide.{{Dofetilide} MedChemExpress|{Dofetilide} Membrane Transporter/Ion Channel|{Dofetilide} Protocol|{Dofetilide} In Vitro|{Dofetilide} supplier|{Dofetilide} Epigenetics} Apalutamide is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM.PMID:34235739 |Product information|CAS Number: 1332391-04-4|Molecular Weight: 464.39|Formula: C20H12F4N4O3S|Chemical Name: 4-{7-[6-cyano-5-(trifluoromethyl)pyridin-3-yl]-8-oxo-6-sulfanylidene-5,7-diazaspiro[3.4]octan-5-yl}-2-fluorobenzoic acid|Smiles: N#CC1=NC=C(C=C1C(F)(F)F)N1C(=S)N(C2=CC(F)=C(C=C2)C(O)=O)C2(CCC2)C1=O|InChiKey: ICXCBGDFYFFSGX-UHFFFAOYSA-N|InChi: InChI=1S/C20H12F4N4O3S/c21-14-7-10(2-3-12(14)16(29)30)28-18(32)27(17(31)19(28)4-1-5-19)11-6-13(20(22,23)24)15(8-25)26-9-11/h2-3,6-7,9H,1,4-5H2,(H,29,30)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|

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