Product Name :
5-Fluorouridine 5′-O-β-D-galactopyranoside
Description:
5-Fluorouridine 5′-O-β-D-galactopyranoside (5′-O-β-D-galactosyl-5-fluorouridine) is a 5-Fluorouridine prodrug. 5-Fluorouridine 5′-O-β-D-galactopyranoside can be converted by the enzyme β-D-galactosidase to the potent antineoplastic agent 5-Fluorouridine.
CAS:
149965-92-4
Molecular Weight:
424.33
Formula:
C15H21FN2O11
Chemical Name:
5-fluoro-1-[(2R,3R,4S,5R)-2-hydrogenio-3,4-dihydroxy-5-({[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
Smiles :
OC[C@H]1O[C@@H](OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=C(F)C(=O)NC2=O)[C@H](O)[C@@H](O)[C@H]1O
InChiKey:
BTPARJRXLUUYJW-FQKYAJAOSA-N
InChi :
InChI=1S/C15H21FN2O11/c16-4-1-18(15(26)17-12(4)25)13-10(23)8(21)6(28-13)3-27-14-11(24)9(22)7(20)5(2-19)29-14/h1,5-11,13-14,19-24H,2-3H2,(H,17,25,26)/t5-,6-,7+,8-,9+,10-,11-,13-,14-/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Kanamycin} medchemexpress|{Kanamycin} Bacterial|{Kanamycin} Technical Information|{Kanamycin} Purity|{Kanamycin} custom synthesis|{Kanamycin} Epigenetic Reader Domain}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
5-Fluorouridine 5′-O-β-D-galactopyranoside (5′-O-β-D-galactosyl-5-fluorouridine) is a 5-Fluorouridine prodrug. 5-Fluorouridine 5′-O-β-D-galactopyranoside can be converted by the enzyme β-D-galactosidase to the potent antineoplastic agent 5-Fluorouridine.|Product information|CAS Number: 149965-92-4|Molecular Weight: 424.33|Formula: C15H21FN2O11|Chemical Name: 5-fluoro-1-[(2R,3R,4S,5R)-2-hydrogenio-3,4-dihydroxy-5-({[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione|Smiles: OC[C@H]1O[C@@H](OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=C(F)C(=O)NC2=O)[C@H](O)[C@@H](O)[C@H]1O|InChiKey: BTPARJRXLUUYJW-FQKYAJAOSA-N|InChi: InChI=1S/C15H21FN2O11/c16-4-1-18(15(26)17-12(4)25)13-10(23)8(21)6(28-13)3-27-14-11(24)9(22)7(20)5(2-19)29-14/h1,5-11,13-14,19-24H,2-3H2,(H,17,25,26)/t5-,6-,7+,8-,9+,10-,11-,13-,14-/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PROTAC-Related Custom Services |Shelf Life: ≥12 months if stored properly.PMID:28630660 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|The ratio of the IC50 of 5-Fluorouridine 5′-O-β-D-galactopyranoside (5′-O-β-D-galactosyl-5-fluorouridine) to that of 5-Fluorouridine determined on a variety of tumor cell lines in vitro ranged from 500:1-1000:1.|In Vivo:|5-Fluorouridine 5′-O-β-D-galactopyranoside (5′-O-β-D-galactosyl-5-fluorouridine) is more than 100x less toxic than 5-Fluorouridine to bone marrow cells in Balb/c mice.|Products are for research use only. Not for human use.|