Product Name :
Thiol-C9-PEG5
Description:
Thiol-C9-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
CAS:
130727-42-3
Molecular Weight:
380.58
Formula:
C19H40O5S
Chemical Name:
23-sulfanyl-3,6,9,12-tetraoxatricosan-1-ol
Smiles :
OCCOCCOCCOCCOCCCCCCCCCCCS
InChiKey:
IOBMVUDHPRVCSO-UHFFFAOYSA-N
InChi :
InChI=1S/C19H40O5S/c20-10-12-22-14-16-24-18-17-23-15-13-21-11-8-6-4-2-1-3-5-7-9-19-25/h20,25H,1-19H2
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Evofosfamide} web|{Evofosfamide} Apoptosis|{Evofosfamide} Technical Information|{Evofosfamide} References|{Evofosfamide} custom synthesis|{Evofosfamide} Epigenetics}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Thiol-C9-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.|Product information|CAS Number: 130727-42-3|Molecular Weight: 380.58|Formula: C19H40O5S|Chemical Name: 23-sulfanyl-3,6,9,12-tetraoxatricosan-1-ol|Smiles: OCCOCCOCCOCCOCCCCCCCCCCCS|InChiKey: IOBMVUDHPRVCSO-UHFFFAOYSA-N|InChi: InChI=1S/C19H40O5S/c20-10-12-22-14-16-24-18-17-23-15-13-21-11-8-6-4-2-1-3-5-7-9-19-25/h20,25H,1-19H2|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.{{Brentuximab} site|{Brentuximab} ADC Antibody|{Brentuximab} Technical Information|{Brentuximab} References|{Brentuximab} supplier|{Brentuximab} Cancer} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:23771862 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|References:|An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562Products are for research use only. Not for human use.|