8 0.44a 69.12 0.50 1.65 0.36 1.55 0.a a ad0.04 0.08a 0.27 0.035 0.15 0.087 0.24 0.076 0.18 0.10 23.06 0.44a 62.27 0.51 eight.61 0.d b ad0.28 0.073c 0.35 0.034 1.21 0.086 0.89 0.073 1.69 0.10 25.66 0.43c 56.64 0.50 six.08 0.c d c5.06 0.075b 0.43 0.04 0.59 0.089 0.61 0.076 0.22 0.ten 20.59 0.44b 53.59 0.51 14.65 0.37 1.12 0.c f b0.004 0.08a 0.56 0.037 n.d. 0.04 0.08 0.11 0.ten 27.91 0.47d 61.64 0.54 0.83 0.39 1.88 0.a b a0.005 0.07a 0.32 0.032 0.07 0.08 0.28 0.070 0.33 0.088 27.84 0.41d 56.39 0.48 5.78 0.34 1.42 0.c d2.51 0.082d 0.45 0.04 0.51 0.ten 1.00 0.082 0.53 0.ten 27.66 0.48d 50.55 0.56 9.92 0.40 1.31 0.e e cP 0.0001 P = 0.36 P = 0.16 P = 0.20 P = 0.82 P 0.0001 P 0.0001 P 0.0001 P = 0.P 0.0001iii P 0.ivP = 0.15 P = 0.EPA[20:five(n-3)] DPA[22:five(n-3)]P 0.0001v P 0.vi1.05 0.083 1.45 0.P = 0.0029 P 0.0001 P = 0.0055 P 0.DHA[22:6(n-3)] SFA MUFA n3PUFA n6PUFAP 0.0001v P 0.0001vii P 0.0001 P 0.viii ixP = 0.30.43 0.49e 51.00 0.56 four.76 0.40 1.66 0.b e1.15 0.1.16 0.P = 0.0046xP = 0.Different letters represent significance among means as determined by Bonferroni correction (P 0.05). Genotype Effect: Lean Obese; Obese Lean. Diet program Impact: iCON, FISH, FLAX SDA; iiFLAX SDA FISH CON; iiiSDA FISH CON, FLAX; ivCON SDA FISH, FLAX; vFISH SDA FLAX, CON; viFISH SDA FLAX CON; FISH SDA; ixSDA FLAX FISH CON; xCON FISH, FLAX, SDA. n.d.- not detectable.viiFISH FLAX, CON SDA;viiiCON FLAX Page ten ofCasey et al. Lipids in Wellness and Illness 2013, 12:147 http://www.lipidworld/content/12/1/Table 7 Subcutaneous adipose tissue fatty acid profile in LZR and OZR rats fed CON, FLAX, FISH, or SDA diets for 12 weeksFatty acid ( of total) LA[18:two(n-6)] ALA[18:3(n-3)] [18:4(n-3)]Lean CON 0.77 0.24 0.63 0.15 0.12 0.ab aObese FISH SDA 0.58 0.24 5.03 0.15 2.66 0.c b d aMain impact FISH SDA 0.66 0.25 three.74 0.15 1.50 0.e c ad aFLAX 0.45 0.24 4.72 0.16 0.12 0.c aCON 0.76 0.25 0.49 0.16 n.d. 0.28 0.021 0.04 0.04a 0.05 0.ab bFLAX 1.16 0.20 three.61 0.12 n.d. 0.20 0.016 0.08 0.03a 0.16 0.c eGenotype P = 0.36 P = 0.0002 P = 0.0011 P = 0.46 P = 0.fDiet P = 0.81 P 0.0001 P 0.0001 P 0.i ii iiiInteraction P = 0.0.57 0.24 1.23 0.14 0.26 0.0.85 0.24 0.92 0.14 0.02 0.P 0.0001 P 0.SDA AA[20:four(n-6)]0.28 0.020 0.06 0.03a 0.04 0.03 n.d. 26.20 1.06 66.50 1.ten 0.87 0.29 1.05 0.a a0.21 0.021 0.08 0.04a 0.01 0.bc0.29 0.020 0.57 0.03cd 0.46 0.e0.36 0.020 0.28 0.04b 0.32 0.d0.25 0.020 0.62 0.03d 0.68 0.029 1.12 0.04e 34.23 1.05 55.Paclitaxel 97 1.Clazosentan 09 3.PMID:36014399 52 0.29 1.10 0.b f0.33 0.021 0.52 0.04c 0.66 0.031 0.33 0.041d 30.42 1.11 56.71 1.15 7.50 0.31 1.00 0.dP = 0.EPA[20:5(n-3)] DPA[22:5(n-3)]P 0.0001v P 0.0001 P = 0.viP 0.0001 P 0.0001 P 0.P 0.0001 P 0.DHA[22:six(n-3)] SFA MUFA n3PUFA n6PUFA0.03 0.04ab 25.55 1.08 63.54 1.12 five.10 0.c0.73 0.04c 27.46 1.05 61.57 1.09 three.42 0.b0.07 0.04ab 24.22 1.09 58.74 1.13 eight.68 0.e0.06 0.04ab 32.27 1.12 62.66 1.16 0.57 0.a0.13 0.033b 31.20 0.88 60.48 0.91 three.98 0.24 1.35 0.bP 0.P 0.0001vviiP = 0.94 P = 0.P = 0.0083 P = 0.084 P = 0.P 0.0001viii P 0.0001 P = 0.ixP = 0.0.66 0.0.86 0.0.94 0.1.04 0.P = 0.Distinctive letters represent significance amongst suggests as determined by Bonferroni correction (P 0.05). Genotype Effect: Lean Obese; Obese Lean. Diet regime Impact: iSDA, FLAX FISH CON; iiSDA FISH, FLAX, CON; iiiSDA FISH, CON FLAX; ivSDA FISH FLAX, CON; vFISH SDA FLAX, CON; viFISH SDA FLAX CON; SDA; ixSDA FLAX FISH CON. n.d.- not detectable.viiFISH CON, FLAX, SDA;viiiCON FLAX FISH,Web page 11 ofCasey et al. Lipids in Overall health and Disease 2013, 12:1.