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The establishment of flow cytometry as the first single cell analysis method with the potential to describe the distribution of cellular properties within a large number of cells has considerably changed our knowledge of cell populations. Before the establishment of flow cytometry our understanding of the immune system was limited to the knowledge that there are leukocytes, monocytes and macrophages, but the complex interplay of the different Band T-cells, effector and killer cells was only resolved when Pepstatin structure monoclonal antibod.