In contrast to RNase A and all other pancreatic-like ribonucleases, which are monomeric in their native point out, BS-RNase is a dimer constituted by two identical subunits linked via two disulfide bridges, as effectively as by non-covalent interactions

A solitary slice was transferred to the recording chamber at a time and constantly superfused with aCSF pre-gassed with ninety five% O2/5% CO2. Extracellular recordings were received at space temperature…